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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177573 | Bim | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human 【克隆 ID】Y36 【用途】WB , IHC , ICC , IP 【抗原分子量】22 kDa |
质量标准: | 【产品介绍】Bim, Bcl-2 interacting mediat o r of cell death, is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members (1). Bim promotes apoptosis by binding to a n d inhibiting the activity of anti-apoptotic Bcl-2 family members, inducing the release of cytochrome c from mitochondria (2). Bim is sequestered in an inactive conf o r mation through binding to the microtubule-associated dynein mot o r complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibit o r y binding to anti-apoptotic Bcl-2 family members a n d subsequent iniation of apoptosis (3,4).
A. Western blot analysis on A431 cell lysate using B. Immunohistochemical analysis of paraffin-embedded |