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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177601 | Caspase-2 | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】Y154 【用途】WB , IP 【抗原分子量】48/18 kDa |
| 质量标准： | 【产品介绍】Caspase-2 (Nedd2/ICH-1) is part of a family of aspartate-specific cysteine proteases that participate in programmed cell death, o r apoptosis. Caspase-2 is localized to the nucleus, a n d has been shown to play roles in both positive a n d negative regulation of apoptosis (1). Upon apoptotic stimulation, pro-caspase-9 is cleaved in a series of steps to produce an 18-kDa large subunit a n d a 12-kDa small fragment (2). Caspase-2 can be a nuclear initiat o r caspase, as it has been shown to precede the processing a n d activation of caspase-8, -9, a n d -3 (3). Caspase-2 might also act as an effect o r caspase; in apoptotic pathways resulting from UV-induced DNA damage, processing of caspase-2 occurs downstream of caspase-9 a n d caspase-3 activation (4).
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