Caspase-3 (active) DyLight® 488 (CASP3)

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Caspase-3 (active) DyLight® 488 (CASP3)

Rabbit Monoclonal Antibody

别名：	CASP3 antibody, CPP32 antibody, CPP32B antibody, SCA-1 antibody, Caspase-3 subunit p12 antibody, Protein Yama antibody, SREBP cleavage activity 1 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177602	Caspase-3 (active) DyLight® 488 (CASP3)	--	100ul	3000元	5天	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】E83-77
【用途】ICC
【抗原分子量】17kDa

质量标准：

【产品介绍】Caspases are a family of cytosolic
aspartate-specific cysteine proteases involved in
the initiation and execution of apoptosis.
Caspase-3 (apopain, SCA-1, Yama and CPP32) is a member
of the apoptosis execution functional group of caspases,
and is either partially or totally responsible for
the proteolytic cleavage of many key proteins
during apoptosis, such as poly (ADP-ribose)
polymerase (PARP) (1,2,3). Caspase-3 is a cytosolic
protein found in cells as an inactive 32 kDa proenzyme.
It is activated by proteolytic cleavage into two
active subunits only when cells undergo apoptosis (3).

Recommended Applications

ICC
Applications and Recommended Dilution Factors

ICC: 1:50 - 100
Species Reactivity

Human

Products Data

Immunofluorescent staining of HeLa without treatment
(left) and HeLa treated with Staurosporine (right)
cells using anti-Caspase-3 (active) antibody conjugated
with Dylight 488 (green, Cat# 4590-1) and Dapi (blue).

Specificity

A synthetic peptide corresponding to residues
following Ser29 of human caspase-3 (N-terminus of
p17 subunit) was used as immunogen. This antibody
only detects the active form of caspase-3 (p17 subunit).

贮存：

Storage Condition and Buffer

Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide,
0.05% BSA. Protect from light. Stable for 6 months from
date of receipt.