CD14_珈得尔化学试剂

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CD14

Rabbit Monoclonal Antibody

别名：	CD14 antibody, - antibody, Monocyte differentiation antigen CD14, membrane-bound form antibody, Myeloid cell-specific leucine-rich glycoprotein antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177613	CD14	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】EPR3652
【用途】IHC , ICC
【抗原分子量】53kDa

质量标准：

【产品介绍】CD14 is a glycophosphatidylinositol-
anchored protein expressed on the surfaces of monocytes
and polymorphonuclear leukocytes. It acts as a
co-receptor for the detection of
bacterial lipopolysaccharide (LPS) (1). CD14 cooperates
with MD-2 and TLR4 to mediate the innate immune response
to bacterial LPS. It acts via MyD88, TIRAP and
TRAF6, leading to NF-kappa-B activation, cytokine
secretion and the inflammatory response (2). CD14
is expressed strongly on peripheral blood monocytes
and macrophages, and weakly on the surface of
granulocytes (1).

Recommended Applications

IHC, ICC
Applications and Recommended Dilution Factors

IHC: 1:100 - 250
ICC: 1:500 - 1000
Species Reactivity

Human

Products Data

Immunohistochemical analysis of paraffin-embedded
human colonic tissue using anti-CD14 RabMAb (cat.# 3890-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-CD14 RabMAb (cat.# 3890-1).

Specificity

A synthetic peptide corresponding to residues in
the extracellular domain of human CD14 was used as
an immunogen.

贮存：

Storage Condition and Buffer

Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.