CD276 (Cd276)_珈得尔化学试剂

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CD276 (Cd276)

Rabbit Monoclonal Antibody

别名：	Cd276 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, CD276 antigen antibody, Costimulatory molecule antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177620	CD276 (Cd276)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human , Mouse
【克隆 ID】EPNCIR122
【用途】WB , FC , IP
【抗原分子量】110kDa

质量标准：

【产品介绍】CD276 is a single-pass type I membrane
protein that modulates T-cell-mediated immune responses
and the development of acute and chronic
transplant rejection. It plays a positive regulatory role
in bone formation and has a dual role in the
bone-immune interface (1). CD276 has been shown to
impair type 1 T-helper cell responses and inhibit
cytokine production (2). Furthermore, it induces
antitumor immunity as it activates both acquired and
innate immunity leading to natural killer cell and
CD8 T-cell dependent killing of tumor cells (1).

Recommended Applications

WB, IP, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IP: 1:10 - 100
FC: 1:10 - 100
Species Reactivity *

Human, Mouse

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) 293T, (B) LnCaP, and (C)
JAR cell lysates using anti-CD276 RabMAb (cat. #5134-1).

Western blot analysis on CD276 knockout CHO cell
lysates, (A) untransfected or (B) transfected with
CD276 using anti-CD276 RabMAb (cat.# 5134-1).

Specificity

Human CD276 recombinant protein and CD276
over-expressing CHO cells were used as an immunogen.

This antibody was developed as part of a
collaboration between Epitomics, the National
Cancer Institute's Center for Cancer Research and the lab
of Brad St. Croix.

贮存：

Storage Condition and Buffer

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt