CEACAM1_珈得尔化学试剂

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CEACAM1

Rabbit Monoclonal Antibody

别名：	CEACAM1 antibody, BGP antibody, BGP1 antibody, BGPI antibody, Carcinoembryonic antigen-related cell adhesion molecule 1 antibody, Biliary glycoprotein 1 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177643	CEACAM1	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】EPR4048
【用途】WB , IHC
【抗原分子量】120-180kDa

质量标准：

【产品介绍】Carcinoembryonic antigen-related cell
adhesion molecule (CEACAM) proteins, members of
the immunoglobulin (Ig) superfamily, are involved
in cell-cell recognition and modulate cellular
processes that range from the shaping of tissue
architecture and neovascularization to the regulation
of insulin homeostasis and T-cell proliferation (1).
CEACAM1 is a type I membrane glycoprotein that plays a
role in intercellular adhesion to inhibit tumor
development as a bacterial adhesin (2). Moreover, CEACAM1
is an active regulator of cell signaling by modulating
the insulin or EGF receptor pathways in epithelial cells
or the Zap-70 pathway in hematopoietic cells (2). It
is known to be a tumor suppressor, since CEACAM1
is down-regulated in most epithelial cell cancers and
T-cell leukemias (3).

Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000-10,000
IHC: 1:100 - 250
Species Reactivity

Human

Products Data

Western blot analysis on (A) HepG2, (B) fetal liver,
and (C) A549 cell lysates using anti-CEACAM1
RabMAb (cat. # 2928-1)

Immunohistochemical staining of paraffin-embedded
human kidney tissue using anti-CEACAM1 RabMAb (cat. #2928-1).

Immunohistochemical staining of paraffin-embedded
human liver tissue using anti-CEACAM1 RabMAb (cat. #2928-1).

Specificity

A synthetic peptide corresponding to residues near
the N-terminus of human CEACAM1 was used as an immunogen.

贮存：

Storage Condition and Buffer

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.