c-Myc DyLight® 488 (MYC)_珈得尔化学试剂

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c-Myc DyLight® 488 (MYC)

Rabbit Monoclonal Antibody

别名：	MYC antibody, MRTL antibody, bHLHe39 antibody, c-Myc antibody, Myc proto-oncogene protein antibody, Proto-oncogene c-Myc antibody, Transcription factor p64 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177657	c-Myc DyLight® 488 (MYC)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】Y69
【用途】ICC
【抗原分子量】57kDa

质量标准：

【产品介绍】Oncogene-encoded proteins c-Myc, N-Myc,
and L-Myc function in cell proliferation,
differentiation and neoplastic disease. Amplification of
the c-Myc gene has been found in several types of
human tumors, the N-Myc gene in neuroblastomas (1), and
the L-Myc gene in human small cell lung carcinomas
(2). c-Myc protein is a transcription factor localized
to the nucleus of the cell. It seems to be involved
in activating the transcription of growth-related
genes. c-Myc binds to DNA during transcription as
a heterodimeric complex with Max. c-Myc is phosphorylated
in vitro by p44/42 MAP kinase at Ser62 (3) and in vivo
at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to
Ala inhibits the ability of c-Myc to activate
transcription (3).

Recommended Applications

ICC
Applications and Recommended Dilution Factors

ICC: 1:50 - 100
Species Reactivity

Human

Products Data

Immunofluorescent staining of HeLa cells using
anti-c-Myc antibody conjugated with Dylight 488
(green, Cat# 4581-1) and Dapi (blue).

Specificity

A synthetic peptide corresponding to residues in
N-terminus of human c-Myc was used as immunogen.

贮存：

Storage Condition and Buffer

Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide,
0.05% BSA. Protect from light. Stable for 6 months from
date of receipt.