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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178961 | HNF4 Alpha DyLight® 488 | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human 【克隆 ID】EPR3648 【用途】ICC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】52kDa |
质量标准: | 【产品介绍】HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein belonging to the steroid hormone receptor superfamily. HNF4 is commonly expressed in the liver and plays a critical role in liver development by establishing and maintaining hepatocyte differentiation (1). In human, two isoforms of HNF4 exists, alpha and gamma. HNF4 alpha is transcriptionally controlled transcription factor, which binds to DNA sites required for the transcription of alpha 1- antitrypsin, Apo CIII, transthyretin genes, and HNF1 alpha (2). HNF4 alpha interacts with PGC-1 to activate gluconeogenesis, leading to lipoprotein metabolism regulation (3). HNF4 alpha defects are known to cause type I diabetes (4). Recommended Applications Products Data Immunofluorescent staining of HepG2 cells using Specificity |
贮存: | Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |