HTR2C_珈得尔化学试剂

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HTR2C

别名：	HTR2C antibody, 5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-hydroxytryptamine receptor 2C antibody, Serotonin receptor 2C antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227178971	HTR2C	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6487
【用途】WB
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】63kDa

质量标准：

【产品介绍】Serotonin (5-hydroxytryptamine, 5-HT),
a neurotransmitter, elicits a wide array of
physiological effects by binding to several
receptor subtypes, including the 5-HT2 family of
seven-transmembrane-spanning, G-protein-coupled
receptors, which activate phospholipase C and D
signaling pathways. HTR2C is the 2C subtype of
serotonin receptor and its mRNA is subject to multiple
RNA editing events, where genomically encoded
adenosine residues are converted to inosines. RNA editing
is predicted to alter amino acids within the
second intracellular loop of the 5-HT2C receptor
and generate receptor isoforms that differ in their
ability to interact with G proteins and the activation
of phospholipase C and D signaling cascades, thus
modulating serotonergic neurotransmission in the
central nervous system. Studies in humans have
reported abnormalities in patterns of HTR2C editing
in depressed suicide victims (1).

Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.
Products Data

Western blot analysis on (A) SH-SY5Y, (B) BxPC-3,
(C) Molt-4, (D) mouse kidney, and (E) rat kidney
lysates using anti-HTR2C RabMAb (cat. #5315-1).

Specificity
A synthetic peptide corresponding to residues near
the C-terminus of human HTR2C was used as an immunogen.

贮存：

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt