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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178973 | Human IgD (IGHD) | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human 【克隆 ID】EPR6146 【用途】WB , IHC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】75kDa |
质量标准: | 【产品介绍】Immunoglobulin (Ig) molecules consist of two chains, one heavy chain and one light chain, each consisting of a variable and a constant region. An IgD molecule contains thus a delta heavy chain combined with either a kappa or lambda light chain. It is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM (1). Secreted IgD might enhance immune protection by regulating B cell homeostasis and activation (2). After the antigen binds to the B-cell receptor, secreted IgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD (1). Recommended Applications Products Data Western blot analysis on human tonsil lysate Immunohistochemical analysis of paraffin-embedded Specificity |
贮存: | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |