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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178978 | IDE | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR6098(2) 【用途】WB , IHC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】120kDa |
质量标准: | 【产品介绍】IDE is a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulin's activity, as well as participating in intercellular peptide signaling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta- amyloid. Deficiencies in IDE's function are associated with Alzheimer's disease and type 2 diabetes mellitus, but mutations in IDE have not been shown to be causative for these diseases. It localizes primarily in the cytoplasm, but in some cell types it localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion (1). Recommended Applications Products Data Western blot analysis on (A) HeLa, (B) HepG2, (C) A375, Immunohistochemical analysis of paraffin-embedded Specificity |
贮存: | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |