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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227178976 | IFN alpha R1 | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR6244 【用途】WB 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】90-130kDa |
| 质量标准： | 【产品介绍】Interferon alpha receptor 1 (IFN alpha R1) is a class II cytokine receptor that belongs to the type I human interferons (IFNs) family. IFNs plays a role in antiviral, antiproliferative, immunomodulatory, antitumor, and antiparasitic activities by inducing transcription of IFN-stimuated genes (ISGs) through activation of the Jak-STAT pathway. Specifically, IFN alpha R1 is a 135-kDa signal transducing subunit of the IFN alpha/beta receptor complex (IFN-α R) (1). IFN alpha R1 is phosphorylated through PTK- and PKC- mediated phosphorylation, which initiates docking of STAT proteins to IFNs. This leads to activation of STAT proteins by PTK-mediated phosphorylation. The mechanism behind the amplification of IFN alpha R complex mediated transmembrane signaling has been linked to tyrosine phosphorylation on IFN alpha R1 (2). Recommended Applications Western blot analysis on (A) HeLa, (B) HeLa treated Specificity |
| 贮存： | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
