IFN gamma_珈得尔化学试剂

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IFN gamma

IFNG

别名：	IFNG antibody, IFG antibody, IFI antibody, Interferon gamma antibody, Immune interferon antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227178977	IFN gamma	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR1108
【用途】WB , ICC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】20-25kDa

质量标准：

【产品介绍】Interferons (IFNs) plays a crucial role
in antiviral, antiproliferative,
immunomodulatory, antitumor, and antiparasitic activities
by inducing transcription of IFN-stimuated genes
(ISGs) through activation of the Jak-STAT pathway.
In particular, Interferon gamma (IFN γ), a sole member
of the Type II IFN family, is involved in
lymphocyte activation and the regulation of
lymphocyte subsets (proliferation, differentiation) (1).
IFN γ is expressed in activated CD4 Th1 cells, CD8
cells, gamma/delta T cells, and activated NK cells.
IFN γ expression is induced by IL-2, TNF-α and IL-12
and suppressed by IL-4, IL-10, and TGF-β (2). IFN γ
binds to IFN γ receptor (IFNGR), which stimulates
various immuno-responses such as macrophages activation
and enhancement of the type I IFNs anti-viral and
anti-tumor activities. In immunocompetent host cells,
IFN γ protects against tumor development and
directs immunogenic phenotype (3). IFN γ has
been implicated in various human diseases, such as
multiple sclerosis and insulin-dependent diabetes
mellitus (4).

Recommended Applications
WB, ICC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:250 - 500
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Molt-4, (B) Jurkat, (C)
lymph node, and (D) human kidney lysates using
anti-IFN gamma RabMAb (cat. #5302-1).

Western blot analysis on 5 ng of IFN gamma
recombinant protein using anti-IFN gamma RabMAb
(cat. #5302-1). Note: molecular weight of
recombinant protein is 17 kDa.

Specificity
A synthetic peptide corresponding to residues in human
IFN gamma was used as an immunogen.

贮存：

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt