Recombinant Human Mannan-binding lectin serine protease 1, His (HEK293-expressed) 是一种在 HEK293 细胞中产生的重组人甘露聚糖结合凝集素丝氨酸蛋白酶1，在 C 末端有 His 标记。甘露聚糖结合凝集素丝氨酸蛋白酶1是一种与体液模式识别分子相关的丝氨酸蛋白酶。
Synonyms
rHuMannan-binding lectin serine protease 1, His; Complement MASP3; MASP-1 ; 重组人甘露聚糖结合凝集素丝氨酸蛋白酶1，His (HEK293-expressed)
Species
HumanSource
HEK 293 Accession
P48740-2 Gene ID
5648 Molecular Weight
Approximately 120.0 kDa AA Sequence
HTVELNNMFG QIQSPGYPDS YPSDSEVTWN ITVPDGFRIK LYFMHFNLES SYLCEYDYVK VETEDQVLAT FCGRETTDTE QTPGQEVVLS PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN YIGGYYCSCR FGYILHTDNR TCRVECSDNL FTQRTGVITS PDFPNPYPKS SECLYTIELE EGFMVNLQFE DIFDIEDHPE VPCPYDYIKI KVGPKVLGPF CGEKAPEPIS TQSHSVLILF HSDNSGENRG WRLSYRAAGN ECPELQPPVH GKIEPSQAKY FFKDQVLVSC DTGYKVLKDN VEMDTFQIEC LKDGTWSNKI PTCKIVDCRA PGELEHGLIT FSTRNNLTTY KSEIKYSCQE PYYKMLNNNT GIYTCSAQGV WMNKVLGRSL PTCLPECGQP SRSLPSLVKR IIGGRNAEPG LFPWQALIVV EDTSRVPNDK WFGSGALLSA SWILTAAHVL RSQRRDTTVI PVSKEHVTVY LGLHDVRDKS GAVNSSAARV VLHPDFNIQN YNHDIALVQL QEPVPLGPHV MPVCLPRLEP EGPAPHMLGL VAGWGISNPN VTVDEIISSG TRTLSDVLQY VKLPVVPHAE CKTSYESRSG NYSVTENMFC AGYYEGGKDT CLGDSGGAFV IFDDLSQRWV VQGLVSWGGP EECGSKQVYG VYTKVSNYVD WVWEQMGLPQ SVVEPQVERH HHHHH Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 200 mM NaCl, 10% Glycerol, pH 8.0. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Human Mannan-binding lectin serine protease 1, His (HEK293-expressed) (rHuMannan-binding lectin serine protease 1, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
Mannan-binding lectin (MBL)-associated serine proteases (MASP-1, -2, and -3) are homologous modular proteases that each associate with MBL and L- and H-ficolins, which are oligomeric serum lectins involved in innate immunity. MASP-1 is a serine protease associated with humoral pattern-recognition molecules and is an abundant component of the lectin pathway of complement. MASP-1 can autoactivate[1][2]. |
